![]() These services give customers the opportunity to instantly benefit from Wingcopter’s cutting-edge technology and its BVLOS (beyond visual line of sight) flight operations track record on five continents without having to own and maintain a fleet of drones, hire and train pilots, or run operations themselves.Ī portion of the new capital is allocated to setting up a partially automated serial production at Wingcopter’s new headquarters in Weiterstadt, Germany, already home to more than 100 employees. In addition to selling drones, Wingcopter will rapidly expand its drone-delivery-as-a-service offerings. To further expand its market reach, Wingcopter is pressing ahead at full speed to launch the next generation of its aircraft, a game-changing delivery drone with unmatched technical specifications. It can accurately lower a package through a winch mechanism, or land at the point of destination and return to its origin with new payload. The current model, the Wingcopter 178 Heavy Lift, provides both one- and two-way delivery, covering distances of up to 120 kilometers. ![]() In addition, Futury Ventures and Hessen Kapital III participated in this financing round. The financing round was led by Silicon Valley-based Xplorer Capital, a key investor in autonomous technologies, and Futury Regio Growth Fund, a Germany-based growth capital fund focusing on investments in globally scalable business models. At the same time, Wingcopter is well-positioned and ready to establish more partnerships worldwide centering around other fully automated delivery applications. ![]() Wingcopter will use the funds to strengthen its leadership in drone-based logistics, with a special focus on healthcare-related applications, including the distribution of COVID-19 vaccines. Weiterstadt, January 25 th, 2021 – Wingcopter, the German developer, manufacturer and operator of unmanned delivery drones for commercial and humanitarian applications, has secured $22 million in Series A funding. ![]()
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![]() ![]() Following intravenous injection, etoposide has a biphasic clearance pattern with half-lives of 3 and 12 h. Both teniposide and etoposide are highly protein bound. Oral administration is characterized by marked intra-patient and interpatient variability, with 40–50% of either drug being absorbed. Epipodophyllotoxins also can inhibit nucleoside transport and impair incorporation of nucleosides into cellular nucleic acids. This is due to the inhibition of topoisomerase II, a nuclear enzyme responsible for the breakage and resealing of DNA. They are cell cycle specific, arresting cells at the S–G 2 interface and causing single strand breaks in DNA. II.B Mechanism of ActionĮpipodophyllotoxins differ from the parent podophyllotoxins, which inhibit microtubule formation due to the glucoside moiety on the C ring of the molecule. Chemical modification of podophyllotoxin by addition of the carbohydrate moieties β- d-thenylidene glucoside and β- d-ethylidene glucoside led to the development of teniposide and etoposide, respectively. Teniposide (VM-26) and etoposide (VP-16-213) are semisynthetic derivatives of podophyllotoxin, an extract of the mandrake plant ( Podophyllum peltatum). Weitberg, in Encyclopedia of Cancer (Second Edition), 2002 II Epipodophyllotoxins II.A Chemistry Peripheral neurotoxicity and hepatotoxicity are rare. Nausea, vomiting, and anorexia are common, as is alopecia, and rash. Toxicitiesĭose-limiting toxicity is myelosuppression, including leukopenia and thrombocytopenia, with nadir at 2 weeks, recovery at 3 weeks. Current indicationsĮtoposide is currently approved in the US as first-line treatment in SCLC (as a combination therapy with a platinum-based agent) and in refractory germ-cell tumors. ![]() Half-life is 6–8 h, and the drug is hepatically metabolized, with 40% renal excretion. Mechanism of actionĮtoposide inhibits topoisomerase II, thereby halting DNA transcription and cell division. Most of the published trials utilize infusional etoposide, but an oral formulation is available as well.Įtoposide is one of the most commonly used anti-cancer agents, as part of standard therapy for SCLC, leukemia/lymphoma, germ-cell tumors, and neuroblastoma. Also known as VP-16, this epipodophyllotoxin is used in SCLC and NSCLC, among many others. Rupard, in Encyclopedia of Respiratory Medicine, 2006 Etoposide (VePesid®, VP-16) OverviewĮtoposide is a semisynthetic derivative of podophyllotoxin, a substance found naturally in the mandrake plant. Resistance mechanisms include decreased expression of DNA topoisomerase II and the multidrugresistant (MDR) phenotype produced by increased expression of the p170 glycoprotein that increases drug efflux, decreasing intracellular accumulation. Etoposide poses an increased risk of secondary malignancies, particularly myelodysplasia and acute myelogenous leukemia associated with chromosome 11:23 translocations within 5 to 8 years of treatment. Adverse effects include myelosuppression, nausea/vomiting, anorexia, alopecia, mucositis, diarrhea, hypersensitivity reactions, fever, bronchospasm, dyspnea, hypotension, and radiation recall skin changes. Etoposide is indicated for the treatment of patients with germ cell tumors, lung cancer, Hodgkin's and non-Hodgkin's lymphomas, gastric cancer, breast cancer, and testicular cancer. Etoposide inhibits topoisomerase II by stabilizing the enzyme–DNA complex and preventing the unwinding of DNA. Gilman, in Cancer Immunotherapy, 2007 1 EtoposideĮtoposide is an alkaloid from the mandrake plant Podophyllum peltatum that has cell cycle-specific activity in the late S phase and G 2 phase. ![]() ![]() What do people say about this website?Īpart from the positive reviews regarding the excellent customer support service, the reviews that this website has are mostly negative rather than positive. Then, this information is personalized into the report given to the customer. The information given by them of your search is compiled from official public records, court documents, government data, and social media. Nonetheless, the website clarifies that they do not make any representation or warranty about the accuracy of the information given of the person looking for. Instant Checkmate is a legitimate business. The third option of how you can unsubscribe from this website is to do it vía mail. Another way to cancel it is through phone number, calling the company’s phone number: (800) 222-8985. The best option is for you to access your account from the official website and go directly to settings and cancel your membership. There are three ways to cancel your membership at Instant Checkmate. This gives the customer wider access to them they have customer service via phone as well as via the internet. The customer support representatives of Instant Checkmate are based in the United States. Meaning that if you´ve been charged for more than 12 months, you will lose your money that exceeds the 12-month refund. If Instant Checkmate has charged you for an extended time and you were not using the service or didn´t cancel your membership, the company will only make a refund of the last 12 months charged. The process of canceling your membership is through their website login, and it is very simple.Ĭharges on your credit card from Instant Checkmate may appear as: Make sure you cancel your membership after you no longer need their services if you don’t want your credit card charged each month without even noticing. Keep an eye on your bank account, after you sign up for a trial or create an account, the service automatically renews you. According to the comments, the membership plan for only one month costs $34.78, and the three-month membership is $83.47. The costs of their service are a bit unclear on the official site, but what is a certainty is that they offer an option of a single month or a three-month membership for their services and that every now and then they give out special offers such as a 5-day trial for only $1.įrom what clients have commented on their reviews, we collected a few data related to the membership plans. Usually, this type of online service requires a monthly subscription, as Instant Checkmate does. People searching for a free background check service will find options, but they won’t receive an accurate report. The website is very clear with this fact and continuously reminds its customers of it.īackground search requires money and, if not time. ![]() The information provided by Instant Checkmate can´t be used for any legal transactions such as: evaluate a person who is asking for a loan or educational help opportunities, hire employees or other purpose subjects for the FCRA. This is an important detail to look at as a consumer. This company is not a consumer reporting agency, and their reports are not defined by the Fair Credit Reporting Act (FCRA). The website offers basic plan information, but you can pay to have a premium membership and have access to more data. Instant Checkmates offers to give clients a Background Check Report with information such as: Still, the difference is that while you may be days in front of the computer looking through the internet to get all the data, Instant Checkmate saves you time by providing certain details faster… Once it gives you all the social media information, you can verify the person you are searching for is the correct match with the pictures posted.Ī single person may find the same information that Instant Checkmate gives you. Instant Checkmate is one of the many websites that offer background checks that include a person’s available public records in the United States.įrom public records search, this website can extract data such as email addresses, phone numbers, criminal records, and social media accounts. If you are looking for a website that does Background Check, you may have come across Instant Checkmate among others, the question you should answer once you find this option to decide whether or not to use it is: Is Instant Checkmate legit? What is the Instant Checkmate website about? How could someone know if the site they are in is a scam? You should do brief research before purchasing something from that website and giving them any personal details. Some websites may not be legit and are just trying to scam you. The amount of choices makes people come up with the question of: Is this site safe? Technology has brought up a lot of options through the internet to people who have access to it. ![]() ![]() ![]() And in addition to being used live, VirtualDJ can also be used to record mixtapes, podcast, or to broadcast to Internet radios. It is used to play live in clubs and big stadiums, at weddings, private parties, or just to train at home. VirtualDJ is used by tens of millions of people every day, ranging from bedroom DJs to international superstars. If you want to change it, our website hosts hundreds of user-made interfaces to replace the default one, or you could easily create your own. And if you want to change any of the default behavior, VirtualDJ has a powerful "VDJScript" language that will let you easily tweak any functions exactly to your liking. VirtualDJ is plug-and-play compatible with most of the DJ controllers that exist on the market. Virtual Dj 8 Mac Crack Download Trainz 2009 Thomas Downloads Scalextric Track Designer Mac Download Insanity Workout Free Download Mac TRAINZ 2006 VERSION. Its built-in sampler will let you spice up your mixes with a broad range of drops and loops, or you can go creative and merge live performance and production by creating remixes on-the-fly by using the sampler like a sequencer. And if you mix videos, you'll also find a lot of video effects and transitions to play with. It comes with a plethora of effects, ranging from traditional flanger, echo, etc, to more modern "beat-aware" effects like beatgrid, slicer, loop-roll. VirtualDJ can play not only audio tracks, but also video or karaoke, if you connect your computer to a projector or the club's screens. And, using the millions of automatic reports we get every day from other VirtualDJ users around the world, it will give you meaningful advices on which songs other DJs consider to go well after what you just played. And if you're missing a track, VirtualDJ will automatically find it on the Internet and stream it directly (*requires an additional subscription). It will let you organize your collection of tracks and group them easily in a DJ-friendly way, using filter to find the hot songs, or find compatible bpm or key, access your previous playlists. ![]() It also lets you scratch your songs, set and recall cues, and all the other regular features DJs expect to find to be able to mix. It lets you "mix" your songs, by playing two or more tracks at the same time, adjust their relative speed so that their tempo will match, apply effects like loops etc, and crossfade from one side to the other. You can now download the VirtualDJ Latest version by doing single click on the given below button of Download.VirtualDJ is a software used by DJs to replace their turntables and CD players, and use digital music instead of vinyl and CDs.
![]() ![]() Right from the start, our vision has been to make more great resources available to web designers for free, and to help creatives to realize their best work. Since our launch, BrushLovers has become a trusted source for fine quality, inspiring Photoshop files. Most of our files are free for both personal and commercial use, so there’s no need to hold back – let your imagination run wild and see what you can create! Some files may come with certain limitations on how they are used, however, so make sure you read the full terms and conditions (included within each file, where available) before adopting them into your project. Our advanced search feature makes it easier than ever to discover the perfect Photoshop brush, style or gradient or texture for your project, or you can browse by category. Our diverse collection of graphic assets is always growing, making BrushLovers the ideal place to find what you need, whatever the style and scope of your work. Whether you're a professional graphic designer looking for fresh ways to wow your clients, or you just love experimenting with all that Photoshop has to offer, BrushLovers has got you covered with all the graphics you need for work or play. You are welcome to link to the the page on our website displaying the brushes, in order to direct others to download them. None of our brushes may be distributed in any shape or form. We limit the download of free brushes to 30 brushes per day per user. Please check this and disable your download manager and the download should then work successfully. It's possible that you have a download manager installed in your browser. Yes, the same brush file can be installed in Adobe Photoshop on both Windows and Mac. They have been tested for compatibility in Photoshop CS, CS2, CS3, CS4 and CS5. ![]() ![]() These brushes will work in Photoshop CS or higher. abr brush file format, we cannot guarantee the results. While they may work in some applications that can read the Photoshop. The brushes are designed to work in Adobe Photoshop only. These brushes may be used for both personal and commercial purposes, provided that the brush files are not distributed in any shape or form. You can install or delete brushes directly from within Brush Pilot. It quickly finds all the brushes on your system and displays a preview of them. If you're a Mac user, we recommend a user friendly application called Brush Pilot. Please click here to see the installation instructions. Why can't I download more than 30 free brushes?Ĭan I distribute the free brushes through my own website or any other way? I cannot download the files, what's wrong? Which version of Photoshop do these brushes work in?ĭo these brushes work on both Mac and Windows? How do I manage and preview multiple brushes?Ĭan I use these brushes for commercial projects?Ĭan I use these brushes in programs besides Photoshop? ![]() ![]() One such story put Tigrett behind Hard Rock's public address microphone after London had been devastated by an Irish Republican Army bombing, announcing to the cafe's patrons that anyone holding an Irish passport could eat and drink for free. A self-described 'raving Marxist,' Tigrett became legendary for his flamboyance and recklessness, renowned for being an eccentric figure who played the principle role in many of the titillating stories composing Hard Rock Cafe lore. Morton was later described as aloof, reserved, and a 'business-first businessman,' personality traits that initially complemented and then later butted against Tigrett's impulsiveness. Outside of youth and family wealth, Tigrett and Morton had little in common. The story of Hard Rock's growth took on a contentious flavor early. The excitement generated by the first cafe, an opening that quickly drew queues of patrons eager to take part in the Hard Rock Cafe's carnival-like atmosphere, was duplicated with each additional opening of restaurants in other cities and other countries, becoming, if anything, more intense, as the restaurants themselves became grander and earned the reputation as popular gathering spots for celebrities. As a restaurateur, Morton was immediately successful, but his first venture was all but forgotten after he hooked up with Tigrett. Morton came from a wealthy and venerable Chicago restaurant family, a heritage he tapped into when he opened The Great American Disaster, an American-style restaurant located in Chelsea, London. Tigrett, son of a wealthy Tennessee financier named John Burton Tigrett, had moved to England with his family at age 15, attended private school in Lugano, Switzerland, and then later spent his days in London selling used Rolls Royces to Americans. They were only 22 years old at the time, and they selected Park Lane in London's fashionable Mayfair district as the site of their 'Hard Rock Cafe.' The decor and menu contrasted sharply with the lavish hotels lining posh Park Lane, where strictly enforced dress codes were the norm, and hamburgers, milk shakes, and the music of the Rolling Stones most certainly were not. Two young Americans, Isaac Tigrett and Peter Morton-who were the quintessential odd couple-borrowed money from their parents to open a quirky restaurant. The popularity of the Hard Rock Cafes grew exponentially from the inception of the first cafe on June 14, 1971, in London. With more than 104 restaurants in 36 countries, as well as three hotel complexes, and the successful 'Hard Rock Live!' television concerts series, the Hard Rock name nearly 30 years later represented a powerful and enduring brand, and a business that was still a dominant force in its industry. Separated by a bitter dispute, the founders later sold their interests and left Rank to put the pieces together. The Rank Group PLC subsidiary was founded in London in 1971 by Isaac Tigrett and Peter Morton. has enjoyed a stellar success that has brought forth several like-minded competitors, including Planet Hollywood, Rainforest Café, and the House of Blues. Without rival for years, themed restaurant phenomenon Hard Rock Cafe International, Inc. ![]() ![]() If you are a big fan of online series and movies, and prefer watching new series and films online, this is the one for you! It offers the best deals to offer you in your leisure time. Also, the list of movies that you can get to see over here, is something that you won't be able to get elsewhere. Not just series, you can easily choose to download and watch all your favorite movies right from here! The best part of 123movies or Movies 123 is that it does not make any compromise in terms of quality. ![]() If you love watching movies online, Movies123 or 123 movies is the most ideal platform for streaming TV series online. Due to several add-ons and features, this streaming site is doing so amazing these days! Having so many streaming platforms on the internet, you might get confused about which one to pick! Well, today we are going to review one of the most famous streaming platforms available to the users. You can now enjoy your favorite movies and shows anytime you want, without having to pay out even a single penny for it. Watching movies in today's times is not a big task anymore. None of the streaming sites succeeded to gain so much popularity since then. ![]() This specific 123 Movies website managed to become the most popular in the world with over 1 million daily visitors at its best moment. The first 123Movies ever created was 123Movies.To who published more than tens of thousands of movies and episodes that could be watched by people from all around the world, for free in HD quality without registration. Wikipedia says that 123movie was created in 2015-2016 but we would suggest this thing happened a few years before the date provided by Wikipedia, from our experience because we've been around the online streaming industry for many years. Movies123 or 123Movies is definitely the most popular free movie streaming platform in the world and it's maintaining its position for a few years already. ![]() ![]() When it’s finished, you’ll get a score, which doesn’t tell much until you compare it with other results. This benchmarks takes the longest because it is the most demanding test out of the three. Of course, you can run the benchmark and then uninstall it to get the space back.Īfter installing 3DMark and running it, you will see that it loads the Time Spy benchmark first. I only suggest running this one on an actual gaming or high-performance workstation because the download is a whopping 3 GB! Mostly it’s just large files for playing back high-resolution graphics for testing, but it eats up a lot of space. The basic edition is free and includes four free benchmarking tests. FutureMark 3DMarkįinally, the other one you should use if you are really wanting to get a proper demanding test done for a high-end gaming machine is Futuremark’s 3DMark benchmark. So the PC above is in the 72nd percentile out of all computers with the same components. The PC benchmarked above is not in the 72nd percentile out of all computers benchmarked using their software. It’s worth noting that the overall percentile score is only against other computers with the same components. If you scroll further down, you’ll also get an overall percentile score and a component-specific percentile score. You’ll see a score for Gaming, Desktop and Workstation performance. It will take a few minutes and then the results will be displayed in a new browser window. What I like about UserBenchmark is that it doesn’t even require any installation. Just download the software and run the EXE file to start the test. This is a good way to see how far you are from the fastest and best computer that has been benchmarked by the Novabench software.Īnother really good program and website is UserBenchmark. ![]() In addition, you can click on Scores & Stats at the very top, which will show you all scores recorded from highest to lowest. ![]() If you click on the View Performance Charts and Comparisons button at the bottom, it will load a web page where you can get your percentile. The results window will give you a Novabench score, which doesn’t mean much on its own unless you are benchmarking your PC several times before and after upgrading the hardware, overclocking, etc. It performs six tests, which can take anywhere from a minute to a few minutes depending on the speed of your system. ![]() ![]() ![]() ![]() Accommodations Are Proactive (Not Retroactive)Īccommodations are proactive, not retroactive. Accommodations do not include non-attendance or non-completion of course and/or program requirements, although the ways of how students satisfy requirements may differ. Environmental adjustments – such as a classroom location, housing configuration, or alternative furniture.Īll these have the purpose of removing barriers and facilitating equal access to the university’s programs and opportunities.Auxiliary aids and services – such as CART and ASL interpreting services, Read&Write text-to-speech application, or note-taking services.Modified materials or procedures – such as braille-formatted texts, additional time to complete exams, or a reduced-distraction setting for testing.Reasonable academic accommodations include things like: ![]() Accommodations Must Be ReasonableĪn accommodation is not considered reasonable if it (a) poses a direct threat to the health or safety of others (b) substantially alters an essential element of a course, curriculum, or program (c) substantially alters the manner in which a service is provided or (d) causes an undue financial or administrative hardship to the university. Requests for accommodations are considered case-by-case, evaluated by disability and any impacts of functional limitations, the reasonableness of the accommodation, and space availability (with regard to housing accommodations). Students are required to live on-campus for four years as part of this commitment to holistic learning this includes students with disabilities to live with others in shared living spaces as an integral part of the Lawrence community. Lawrence University believes the learning experience in a community living model is essential to student growth. Housing accommodations are considered as part of the campus residency requirement. As a college student, you must carefully manage your time and devote substantial effort to your studies to succeed academically. Academic accommodations are intended to provide access and they are no guarantee of success. Academic accommodations give students with disabilities the opportunity to learn and to demonstrate their learning without undue limitation by factors related to barriers in the academic environment and the disability. ![]() ![]() The exception is when all the species that make up the flock are still in the same related family. The more unique, specialized terms, however, are only used for single-species flocks. Species: Any large group of birds, no matter how many different species make up the group, can be called a flock if only a general flock term is used.Less social birds, however, such as hummingbirds or grosbeaks, would be considered a flock if there were only a few birds since they are much less likely to gather in larger groups. For example, gregarious birds such as gulls, ducks, and starlings are often seen in very large groups, so just a half dozen of these birds together would not usually be called a flock. ![]() In general, larger groups are always considered flocks, while smaller groups may be flocks if the birds are not often seen in groups. But there is no set minimum number of birds that are needed to call a group a flock. Just two or three birds are not usually a flock. Numbers: Counting birds can give you a hint. ![]() The Spruce Home Improvement Review Board.These examples are programmatically compiled from various online sources to illustrate current usage of the word 'flock.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. 2022 Mastodon is experiencing a rapid rise in users, as Twitter users flock to it. 2022 Opened as a tourist attraction in 2006, fans continue to flock to the city to visit A Christmas Story House & Museum every year. Isabel Debre, The Christian Science Monitor, 23 Nov. 2022 But another sport is flying high in the historic center of the capital, Doha, as over a million foreign fans flock to the tiny emirate: falconry. Amanda Pérez Pintado, USA TODAY, 27 Nov. 2022 The fleet of vehicles being discontinued in 2022 includes a number of passenger cars such as the Chevrolet Spark, the Toyota Avalon and the Honda Insight, as Americans continue to flock to SUVs. 2022 Airline performance has struggled over the past year as passengers flock back to the skies. 2023 So long as the brand continues to commit to quality, Wagstaff says customers will continue to flock back to its stores. Georgina Lawton, Travel + Leisure, 25 Jan. ![]() 2023 This is perhaps why honeymooners and couples continue to flock here in droves, despite the heftier price tags. Verb Police are 'outnumbered' Each March, tens of thousands of people flock to Miami Beach to take in Florida’s sunshine and party. 2023 Hiding eggs is a trait my flock inherited from their ancestors. 2023 Missouri not only had a healthy, growing flock of the Eastern subspecies in the mid-1970s but was willing to share its wealth with other states. 2023 Two reports of golden eagles in western Massachusetts came in along with small numbers of bohemian waxwings continuing to be seen among a large flock of cedar waxwings in North Adams. 2023 But egg supplies overall are holding up because the total flock of egg-laying hens is only down about 5% from from its normal size of around 320 million hens. 2023 Every January, decorators and interior designers from around the world flock to the streets of Paris for a dose of inspiration at Paris Deco-Off courtesy of the more than 100 brands which set up shop to exhibit their latest wallpapers, wall decor, and fabrics. 2023 But a series of scandals have affected the church’s popularity, and some of its high-profile members, like pop star Justin Bieber, have left the flock. 2023 Its hybrid format assures that as one festival winds down, another winds up-the flocks of filmgoers suddenly replaced by music lovers arriving to catch a show or 10. Noun Small agreed that abuse survivors, as well as the broader Catholic flock, must at the very least be informed of case outcomes. ![]() |